Select multiple nodes at once
Building a topology is faster when you can act on several devices at once. Drag a box across empty canvas to marquee-select every device inside, then move, align or delete them together instead of one at a time.
Drag a box across empty canvas to marquee-select - every device inside is selected together. Shift-click adds or removes individual nodes from the selection instead.
Marquee-select plus alignment is how you tidy a sprawling topology quickly - it works on annotations too, not just devices. See "Undo and redo on the canvas" for stepping back from a mistake made while moving a selection.